Medicine is a special commodity. Its efficacy and quality are directly related to human health and safety. The packaging materials used not only ensure the efficacy, but also ensure the reliability and convenience of medicine use.
It is an industry with increasingly strict quality requirements, and several trends are expected in the future:
Green: develop new degradable packaging materials.
Environmental regulation: pharmaceutical blister Alu foil can change the gas state in the package and ensure the quality of packaged products for a long time. For example, there are packages sealed with desiccant (oxygen getter) to extend the shelf life of drugs.
Flexible packaging: thermoformed extruded blister packaging with controllable dose, which will replace the packaging of bulk or bottled drugs.
High barrier: use materials with excellent barrier to prevent gas, water vapor, odor and light from entering the package, so as to ensure the effectiveness of drugs. The application of high barrier packaging has been very common in Europe and Japan.
Asepsis: a packaging method for sterilization of packaged drugs in a sterile environment using instant ultra-high temperature sterilization technology. Composite materials are used for packaging through different forms of extrusion and composite molding.
Drugs are special commodities. The sealing of packaging is very important, which can protect drugs from moisture, ensure drug quality and curative effect, and also affect the storage cycle of drugs.
For unqualified drugs, moisture is one of the common reasons. Generally, it is caused by the lax packaging of drugs and moisture absorption in the process of storage and circulation. Blister packaging of drugs is one of the main packaging methods of drugs because of its good sealing and convenient use and carrying.
The materials used for blister packaging are mainly PTP medicinal aluminum foil and plastic hard sheet. Polyvinyl chloride (PVC), polyvinylidene chloride (PVDC) or composite materials are usually used as plastic hard sheet materials.
Polyvinylidene chloride film (PVDC) is a kind of film with the best barrier performance. It has barrier performance and chemical stability to oxygen, water vapor, carbon monoxide and organic compounds. Among many polymer pharmaceutical packaging materials, only PVDC has high barrier performance to water vapor and oxygen at the same time, which has been widely used in pharmaceutical packaging.
In high barrier pharmaceutical packaging, it is usually used as coating material. 2-4m PVDC composite film is coated on PP, CPE and PET film, which can play the role of moisture resistance, flavor preservation and moisture resistance. PVDC is the most common coating in blister packaging. It can reduce the air permeability and moisture permeability of PVC blister packaging by 5-10 times. PVDC coated composite film for medicine is used to make high-temperature cooking sterilization bags and fresh-keeping and anti-corrosion bags in China.
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